DOASENSE - Products & Technology - Pioneering Point-of-Care Testing for DOACs

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Our Products & Technologies

Using our sophisticated technologies for assessing DOAC in urine we create unique products, providing meaningful data to health care professionals, all in an easy, rapid assessment process

The DOAC Dipstick Product

We have developed the first point-of care testing system which can detect reliably and accurately whether a patient has taken Direct Oral Anti-Coagulants (“DOACs”), e.g. in an emergency setting where every minute counts: the DOAC Dipstick.

DOAC Dipstick is a diagnostic urine test strip, which is intended for qualitative detection of the absence or presence of direct oral anticoagulants (DOACs: Dabigatran, Apixaban, Edoxaban and Rivaroxaban) in human urine by visual identification of colors.
The DOAC Dipstick is an in vitro diagnostic test intended for professional use only. It has received the CE Mark in 2018. One DOAC Dipstick pack includes 12 tests (test strips).

The DOAC Dipstick point-of-care test is now commercially available in Germany through HITADO [ORDER HERE] / Der DOAC Dipstick Point-of-Care-Test ist nun in Deutschland über HITADO erhältlich [BESTELLEN SIE HIER]

By its rapid, qualitative point-of-care testing, use of the DOAC Dipstick can support medical decision-making and help avoiding uncontrolled, potentially fatal bleeding, e.g. in emergency care situations or in surgical interventions.

DOACs are excreted to a large extent into urine by glomerular filtration and a urine-based test can provide greater accuracy than a blood test, as there are no adversely interacting proteins or blood cells. Thus, for our urine-based DOAC Dipstick test a high sensitivity and specificity has been demonstrated (see below).

The technique allows to identify the absence or presence of:
  • Direct oral Thrombin inhibitors  (Dabigatran - pad #4)
  • Direct oral Factor Xa inhibitors  (Apixaban, Edoxaban and Rivaroxaban - pad #3)
  • Urine color  (for avoiding that dark urine colors impact the DOAC test results - pad #2)
  • Creatinine  (for avoiding that renal insufficiencies impact the DOAC test results - pad #1)
by means of color changes based on a chemical reaction.
Results are ready after 10 min and are obtained by color identification with the naked eye:

The DOAC Dipstick can contribute important data in many situations when it is essential to be aware of the presence or absence of DOACs for further medical decision making and therapy planning, e.g.:
  • Ischemic and haemorrhagic stroke
  • Major trauma
  • Emergency procedures
  • Spontaneous thrombotic and  bleeding events
  • Acute surgery or invasive interventions
  • Indication for thrombolytic therapy
  • Known of suspicion of deterioration of renal function
  • Very elderly patients
  • Adherence to therapy
  • Unknown medical history

How the DOAC Dipstick works:
DOASENSE Technology Animation

Listen to what opinion leaders think about DOASENSE's solutions:    (in German)

Our Data

Data on the DOAC Dipstick
Here you can find first published data on the DOAC Dipstick.

More data on our underlying DOAC sensing technologies
  • Global Study Data (13 Centers), from: Harenberg J, et al., Clin Chem Lab Med. 2016 Feb 1; 54(2):275-83
Study Data
Our Intellectual Property

DOASENSE has compiled and owns a broad portfolio of international intellectual property for protecting its proprietary approaches to DOAC testing.
NOTE: DOASENSE(TM) products may not be available or approved in your country.

Copyright (c) 2016-2019 DOASENSE GmbH. All rights reserved.
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